TCI Home
 

TCI Chemistry News   July 2021

 
 

 

 
TCI offers an extensive catalog of 30,000 high quality organic reagents suitable for benchtop-to-bulk chemistry. This issue covers our chemistry expertise in organophosphorus catalysts, a ruthenium catalyst in coupling reaction of alcohols with primary amines, an easy to handle silylating reagent with high reactivity, and olefin metathesis using nitro-Grela.
Organophosphorus Catalysts

Organophosphorus Catalysts

TCI offers useful organophosphorus catalysts which are stable solids and easy-to-handle. 2-[(Diphenylphosphoryl)methyl]phenol [H1763] catalyzes the Mitsunobu-type reaction and is generally waste-free. anti-1,2,2,3,4,4-Hexamethylphosphetane 1-oxide [H1766] catalyzes deoxygenative C-N cross coupling of nitro(hetero)arenes with (hetero)arylboroic acids to form di(hetero)arylamines. MeTAPS-Br [H1748] and MeTAPS-I [H1749] catalyzes carbon dioxide fixation reaction under ambient pressure.
Read More
Ruthenium Catalyst in Coupling Reaction of Alcohols with Primary Amines

Ruthenium Catalyst in Coupling Reaction of Alcohols with Primary Amines

Chloro(p-cymene)[2-[(di-tert-butylphosphino)methyl]pyridine]ruthenium(II) triflate [C3668] catalyzes the reaction of benzyl alcohol derivatives with primary amines to yield secondary amines. The advantage of this reaction is that it does not require any additives or solvents. Apparently, chemoselective dehydration condensation of benzyl alcohol derivatives with primary amines can proceeds even in the presence of unprotected phenols or anilines. In addition, it has been reported that the tandem Pictet-Spengler reaction of alcohols and N-benzyltryptamines affords tetrahydro-β-carbolines in presence of C3668 and a Lewis acid catalyst like In(OTf)3.
Read More
Easy to Handle Silylating Reagent with High Reactivity

Easy to Handle Silylating Reagent with High Reactivity

Organosilicon compounds are frequently used in synthetic chemistry and material science, due to their unique chemical reactivity and potential functional utility. Yorimitsu et al. recently reported the utility of 1,2-di-tert-butoxy-1,1,2,2-tetramethyldisilane [D5736] which is stable in the air and can be easily handled, as a useful silylating reagent. It is also unique and very useful in silylating reactions. For example, copper-catalyzed ring-opening silylation of benzofurans with D5736 affords (E)-o-(β-silylvinyl)phenols with complete E/Z selectivity and high yields under mild conditions. In addition, the coupling reaction of a series of chloroarenes and D5736 using SingaCycle™-A3 as a precatalyst results in the corresponding silylarenes in high yields.
Read More
TCI Practical Example: Olefin Metathesis Using nitro-Grela

TCI Practical Example: Olefin Metathesis Using nitro-Grela

TCI introduces the ring-closing metathesis using nitro-Grela [N1060] as a catalyst. The reaction report is actually performed by TCI's synthesis staff. You can see not only the reaction procedure but also the comment and analysis data from our staff.
Read More
 

Follow Us on Social Media

Facebook
Instagram
LinkedIn
Twitter

How to Order TCI Products

To order, please contact your local distributor found below.

Countries/ Regions:

Singapore
Taiwan
Australia
South Korea
Other Asia Pacific / Regions

» TCI eNewsletter Back Issues

* The prices displayed in the landing website are USD based catalog prices.  TCI has specific website and local currency based price list for customers in South Korea, Singapore, and Australia.  For customers in other Asia Pacific countries / regions, please visit our Asia Pacific Website and contact our local distributors for the end user's cost. (The USD prices that are shown in Asia Pacific websites are TCI's catalog prices.)
Please visit each country/region's website from the following links and confirm the prices. 
https://www.TCIchemicals.com
 


Tokyo Chemical Industry Co., Ltd. (TCI)
Global Business Department
Customer Support and Technical service

» globalbusiness@TCIchemicals.com
» https://www.TCIchemicals.com
?


Connect with TCI

Facebook_S Twitter_S Linkedin_S Instagram_S TCI_S

Copyright © 2021
Tokyo Chemical Industry Co., Ltd.
4-10-2 Nihonbashi-honcho, Chuo-ku,Tokyo 103-0023 Japan
E-mail: TCIeNewsletter@TCIchemicals.com


Privacy Policy