September Chemistry News
 

TCI Chemistry News September 2020

 
 

 

 

TCI offers an extensive catalog of 30,000 high quality organic chemicals suitable for benchtop-to-bulk chemistry. This issue covers our chemistry expertise in diamidite for the synthesis of phosphodiesters, a versatile reagent for sulfoximidation, quaternary ammonium salts, the Pauson-Khand reaction, and more.

Diamidite for the Synthesis of Phosphodiesters

Diamidite for the Synthesis of Phosphodiesters

Benzyl N,N,N',N'-tetraisopropylphosphorodiamidite [B5997] is used in the synthesis of phosphodiesters and phosphorylation of inositols and nucleosides. B5997 promptly reacts with alcohols in the presence of a base like 1H-tetrazole to afford a phosphoramidite. It can further react with another alcohol resulting in a phosphite triester with different alcohol species. Successive oxidation of the phosphorus atom and deprotection gives a phosphodiester.

Read More
Versatile Reagent for Sulfoximidation

Versatile Reagent for Sulfoximidation

Dimethylsulfoximine [D4971] is a building block for the synthesis of sulfoximines and utilized in various types of sulfoximidation reactions. Possible applications include as SN2 reactions, nucleophilic attacks to carbonyl groups and cross-coupling reactions, providing  the target compounds in high yields under various conditions. Furthermore, this functional group can be inserted at a late stage of complex syntheses via C-H activation.
Read More
Quaternary-Ammonium-Salts

Quaternary Ammonium Salts

Quaternary ammonium salts are organic compounds in which the ammonia molecule is tetrasubstituted with carbon and has a cationic state. A lot of quaternary ammonium salts have been synthesized and various applications have been reported in the literature. For example, in organic chemistry, tetramethylammonium hydroxide (TMAH) [T0676] as a methyl esterification agent, tetraethylammonium hydroxide (TEAH) [I0363] as an ion-pair reagent, tetrabutylammonium hydroxide (TBAOH) [T0717] as a polymerization catalyst, and benzyltriethylammonium chloride (BTEAC) [B0444] as a phase transfer catalyst have been reported.

Read More
Pauson-Khand Reaction

Pauson-Khand Reaction

The Pauson-Khand reaction is a [2+2+1] type cyclization reaction used to construct a cyclopentenone moiety from alkynes and alkenes, mediated by dicobalt octacarbonyl [D3213]. Alkynes have high affinity towards D3213 and form an alkyne-dicobalt intermediate which can be isolated. This intermediate then coordinates with an alkene followed by CO insertion to afford the cyclic product. In many cases, the Pauson-Khand reaction is used in the total synthesis of natural products bearing a cyclopentanone moiety.
Read More
 

Follow Us On Social Media

Facebook
Instagram
LinkedIn
Twitter

How to Order TCI Products

For order, please contact our local distributors as follow.

SEJIN CI (Exclusive Distributor)
20, Sinmok-ro, Yangcheon-gu, Seoul,
08015, Korea
Tel: 02-2655-2480
Fax: 0505-500-2480
» sales@sejinci.co.kr
» https://www.sejinci.co.kr/

* The prices displayed in the landing website are USD based catalog prices.  TCI has specific website and local currency based price list for customers in South Korea, Singapore, and Australia.  For customers in other Asia Pacific countries / regions, please visit our Asia Pacific Website and contact our local distributors for the end user's cost. (The USD prices that are shown in Asia Pacific websites are TCI's catalog prices.)
Please visit each country/region's website from the following links and confirm the prices. 
https://www.TCIchemicals.com
 


Tokyo Chemical Industry Co., Ltd. (TCI)
Global Business Department
Customer Support and Technical service

» globalbusiness@TCIchemicals.com
» https://www.TCIchemicals.com


Connect with TCI

Facebook_S Twitter_S Linkedin_S Instagram_S TCI_S

Copyright © 2020
Tokyo Chemical Industry Co., Ltd.
4-10-2 Nihonbashi-honcho, Chuo-ku,Tokyo 103-0023 Japan
E-mail: TCIeNewsletter@TCIchemicals.com


Privacy Policy